The p38α MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice.

The p38α MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice.

p38 MAPK activity plays an important role in several steps of the osteoblast lineage progression through activation of osteoblast-specific transcription factors and it is also essential for the acquisition of the osteoblast phenotype in early development. Although reports indicate p38 signalling pla...

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Bibliographic Details
Main Authors: Edgardo Rodríguez-Carballo, Beatriz Gámez, Lara Sedó-Cabezón, Manuela Sánchez-Feutrie, Antonio Zorzano, Cristina Manzanares-Céspedes, José Luis Rosa, Francesc Ventura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4090229?pdf=render

Internet

http://europepmc.org/articles/PMC4090229?pdf=render

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