Exosomes derived from mesenchymal stem cells enhance radiotherapy-induced cell death in tumor and metastatic tumor foci

Exosomes derived from mesenchymal stem cells enhance radiotherapy-induced cell death in tumor and metastatic tumor foci

Abstract Background We have recently shown that radiotherapy may not only be a successful local and regional treatment but, when combined with MSCs, may also be a novel systemic cancer therapy. This study aimed to investigate the role of exosomes derived from irradiated MSCs in the delay of tumor gr...

Full description

Bibliographic Details
Main Authors: Virgínea de Araujo Farias, Francisco O’Valle, Santiago Serrano-Saenz, Per Anderson, Eduardo Andrés, Jesús López-Peñalver, Isabel Tovar, Ana Nieto, Ana Santos, Francisco Martín, José Expósito, F. Javier Oliver, José Mariano Ruiz de Almodóvar
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Molecular Cancer
Subjects:
Experimental radiotherapy
Bystander effect
Abscopal effect
Mesenchymal stem cells
Cell therapy
Metastasis spread
Online Access:http://link.springer.com/article/10.1186/s12943-018-0867-0

Internet

http://link.springer.com/article/10.1186/s12943-018-0867-0

Similar Items