COX-2 INHIBITION REDUCES BRUCELLA BACTERIAL BURDEN IN DRAINING LYMPH NODES

Brucella is a Gram-negative facultative intracellular bacterium responsible for a chronic disease known as brucellosis, the most widespread re-emerging zoonosis worldwide. Establishment of a T helper 1 (Th1)-mediated immune response characterized by the production of IL-12 and IFNγ is essential to c...

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Bibliographic Details
Main Authors: Aurélie Gagnaire, Laurent Gorvel, Alexia Papadopoulos, Kristine Von Bargen, Jean-louis Mege, Jean-Pierre Gorvel
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01987/full