Real time identification of drug-induced liver injury (DILI) through daily screening of ALT results: a prospective pilot cohort study.

Identification of drug-induced liver disease (DILI) is difficult, even among hospitalized patients. The aim of this pilot study was to assess the impact of a specific strategy for DILI screening.We prospectively compared the number of acute DILI cases identified in one week of a proactive strategy b...

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Main Authors: Helmi M'Kada, Hugo Perazzo, Mona Munteanu, Yen Ngo, Nittia Ramanujam, Bruno Fautrel, Françoise Imbert-Bismut, Vlad Ratziu, Ina Schuppe-Koistinen, Véronique Leblond, Jean Yves Delattre, Yves Samson, Olivier Lyon Caen, François Bricaire, David Khayat, Charles Pierrot-Deseilligny, Serge Herson, Zahir Amoura, Patrick Tilleul, Olivier Deckmyn, Pierre Coriat, Vincent Nicolas Delpech, Philippe Boulogne, Dominique Bonnefont-Rousselot, Thierry Poynard, Drug Induced Liver Injury Groupe Hospitalier Pitié-Salpêtrière Group, Safer and Faster Evidence-based Translation Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3419230?pdf=render