The Performance of Gene Expression Signature-Guided Drug–Disease Association in Different Categories of Drugs and Diseases

The Performance of Gene Expression Signature-Guided Drug–Disease Association in Different Categories of Drugs and Diseases

A gene expression signature (GES) is a group of genes that shows a unique expression profile as a result of perturbations by drugs, genetic modification or diseases on the transcriptional machinery. The comparisons between GES profiles have been used to investigate the relationships between drugs, t...

Full description

Bibliographic Details
Main Authors: Xiguang Qi, Mingzhe Shen, Peihao Fan, Xiaojiang Guo, Tianqi Wang, Ning Feng, Manling Zhang, Robert A. Sweet, Levent Kirisci, Lirong Wang
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
gene expression signature
drug repositioning approaches
RNA expression regulation
Online Access:https://www.mdpi.com/1420-3049/25/12/2776

Internet

https://www.mdpi.com/1420-3049/25/12/2776

Similar Items