Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains

G-quadruplexes (G4s), which are structures formed in guanine-rich regions of DNA, are involved in a variety of significant biological functions, and therefore “sequence-dependent” selective G4-stabilizing agents are required as tools to investigate and modulate these functions. H...

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Bibliographic Details
Main Authors: Yue Ma, Keisuke Iida, Shogo Sasaki, Takatsugu Hirokawa, Brahim Heddi, Anh Tuân Phan, Kazuo Nagasawa
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/24/2/263