The dimeric structure of wild-type human glycosyltransferase B4GalT1.

Most glycosyltransferases, including B4GalT1 (EC 2.4.1.38), are known to assemble into enzyme homomers and functionally relevant heteromers in vivo. However, it remains unclear why and how these enzymes interact at the molecular/atomic level. Here, we solved the crystal structure of the wild-type hu...

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Bibliographic Details
Main Authors: Deborah Harrus, Fawzi Khoder-Agha, Miika Peltoniemi, Antti Hassinen, Lloyd Ruddock, Sakari Kellokumpu, Tuomo Glumoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6198961?pdf=render