Predominance of Dystrophinopathy Genotypes in Mexican Male Patients Presenting as Muscular Dystrophy with A Normal Multiplex Polymerase Chain Reaction <i>DMD</i> Gene Result: A Study Including Targeted Next-Generation Sequencing

Predominance of Dystrophinopathy Genotypes in Mexican Male Patients Presenting as Muscular Dystrophy with A Normal Multiplex Polymerase Chain Reaction <i>DMD</i> Gene Result: A Study Including Targeted Next-Generation Sequencing

The complete mutational spectrum of dystrophinopathies and limb-girdle muscular dystrophy (LGMD) remains unknown in Mexican population. Seventy-two unrelated Mexican male patients (73% of pediatric age) with clinical suspicion of muscular dystrophy and no evidence of <i>DMD</i> gene dele...

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Bibliographic Details
Main Authors: Miguel Angel Alcántara-Ortigoza, Miriam Erandi Reyna-Fabián, Ariadna González-del Angel, Bernardette Estandia-Ortega, Cesárea Bermúdez-López, Gabriela Marisol Cruz-Miranda, Matilde Ruíz-García
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Genes
Subjects:
duchenne/becker muscular dystrophies
dilated cardiomyopathy
limb-girdle muscular dystrophies
neuromuscular disorders
mexican population
next-generation sequencing
Online Access:https://www.mdpi.com/2073-4425/10/11/856

Internet

https://www.mdpi.com/2073-4425/10/11/856

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