Arginine Derivatives in Cerebrovascular Diseases: Mechanisms and Clinical Implications

The amino acid L-arginine serves as substrate for the nitric oxide synthase which is crucial in vascular function and disease. Derivatives of arginine, such as asymmetric (ADMA) and symmetric dimethylarginine (SDMA), are regarded as markers of endothelial dysfunction and have been implicated in vasc...

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Bibliographic Details
Main Authors: Gerrit M. Grosse, Edzard Schwedhelm, Hans Worthmann, Chi-un Choe
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/5/1798