Transcriptional regulation of PP2A-A alpha is mediated by multiple factors including AP-2alpha, CREB, ETS-1, and SP-1.

Protein phosphatases-2A (PP-2A) is a major serine/threonine phosphatase and accounts for more than 50% serine/threonine phosphatase activity in eukaryotes. The holoenzyme of PP-2A consists of the scaffold A subunit, the catalytic C subunit and the regulatory B subunit. The scaffold subunits, PP2A-A...

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Bibliographic Details
Main Authors: He-Ge Chen, Wen-Jun Han, Mi Deng, Jichao Qin, Dan Yuan, Jin-Ping Liu, Ling Xiao, Lili Gong, Songping Liang, Jian Zhang, Yun Liu, David Wan-Cheng Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2736573?pdf=render