Expanded complement of Niemann-Pick type C2-like protein genes in Clonorchis sinensis suggests functions beyond sterol binding and transport

Expanded complement of Niemann-Pick type C2-like protein genes in Clonorchis sinensis suggests functions beyond sterol binding and transport

Abstract Background The parasitic flatworm Clonorchis sinensis inhabits the biliary tree of humans and other piscivorous mammals. This parasite can survive and thrive in the bile duct, despite exposure to bile constituents and host immune attack. Although the precise biological mechanisms underlying...

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Bibliographic Details
Main Authors: Marziyeh Anari, Andreas J. Stroehlein, Ross S. Hall, Bill C. H. Chang, Robin B. Gasser, Neil D. Young
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Parasites & Vectors
Subjects:
Clonorchis sinensis
Comparative genomics
Niemann-pick type C2
NPC2
Functional protein annotation
Adaptation
Online Access:https://doi.org/10.1186/s13071-020-3910-0

Internet

https://doi.org/10.1186/s13071-020-3910-0

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