RocA Regulates Phosphatase Activity of Virulence Sensor CovS of Group A Streptococcus in Growth Phase- and pH-Dependent Manners

The emergence of invasive group A streptococcal infections has been reported worldwide. Clinical isolates that have spontaneous mutations or a truncated allele of the rocA gene (e.g., emm3-type isolates) are considered to be more virulent than isolates with the intact rocA gene (e.g., emm1-type isol...

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Bibliographic Details
Main Authors: Chuan Chiang-Ni, He-Jing Chiou, Huei-Chuan Tseng, Chih-Yun Hsu, Cheng-Hsun Chiu
Format: Article
Language:English
Published: American Society for Microbiology 2020-05-01
Series:mSphere
Subjects:
ph
Online Access:https://doi.org/10.1128/mSphere.00361-20