Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus

Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus

Abstract Background Hypothalamic inflammation including astrogliosis and microglia activation occurs after intake of high fat diet (HFD) in rodent models or in obese individuals. However, the effect of chronic HFD feeding on oligodendrocytes (OLGs), a myelin-producing glial population in the central...

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Main Authors: Hui-Ting Huang, Sheng-Feng Tsai, Hung-Tsung Wu, Hsin-Ying Huang, Han-Hsueh Hsieh, Yu-Ming Kuo, Po-See Chen, Chung-Shi Yang, Shun-Fen Tzeng
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Neuroscience
Subjects:
Oligodendrocytes
Myelin
IL-33
Glia
Microglia
Obesity
Online Access:http://link.springer.com/article/10.1186/s12868-019-0516-6

Internet

http://link.springer.com/article/10.1186/s12868-019-0516-6

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