Polycaprolactone nanofiber scaffold enhances the osteogenic differentiation potency of various human tissue-derived mesenchymal stem cells

Polycaprolactone nanofiber scaffold enhances the osteogenic differentiation potency of various human tissue-derived mesenchymal stem cells

Abstract Background Polycaprolactone (PCL) has been regarded as a promising synthetic material for bone tissue engineering application. Owing to its unique biochemical properties and great compatibility, PCL fibers have come to be explored as a potential delivering scaffold for stem cells to support...

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Bibliographic Details
Main Authors: Ruyue Xue, Yuna Qian, Linhao Li, Guidong Yao, Li Yang, Yingpu Sun
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Stem Cell Research & Therapy
Subjects:
Polycaprolactone
Mesenchymal stem cells
Osteogenic differentiation
Wnt/β-catenin signaling pathway
Smad3
Online Access:http://link.springer.com/article/10.1186/s13287-017-0588-0

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http://link.springer.com/article/10.1186/s13287-017-0588-0

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