Mechanism of the pH-induced conformational change in the sensor domain of the DraK Histidine kinase via the E83, E105, and E107 residues.

Mechanism of the pH-induced conformational change in the sensor domain of the DraK Histidine kinase via the E83, E105, and E107 residues.

The DraR/DraK two-component system was found to be involved in the differential regulation of antibiotic biosynthesis in a medium-dependent manner; however, its function and signaling and sensing mechanisms remain unclear. Here, we describe the solution structure of the extracellular sensor domain o...

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Bibliographic Details
Main Authors: Kwon Joo Yeo, Young-Soo Hong, Jun-Goo Jee, Jae Kyoung Lee, Hyo Jeong Kim, Jin-Wan Park, Eun-Hee Kim, Eunha Hwang, Sang-Yoon Kim, Eun-Gyeong Lee, Ohsuk Kwon, Hae-Kap Cheong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4159317?pdf=render

Internet

http://europepmc.org/articles/PMC4159317?pdf=render

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