Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease

Unfolded stress response (UPR) is a conserved cellular pathway involved in protein quality control to maintain homeostasis under different conditions and disease states characterized by cell stress. Although three general schemes of and genes induced by UPR are rather well-established, open question...

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Bibliographic Details
Main Authors: Dan Lindholm, Laura Korhonen, Ove Eriksson, Sulev Kõks
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
UPR
Online Access:http://journal.frontiersin.org/article/10.3389/fcell.2017.00048/full