Synchronized Cell Cycle Arrest Promotes Osteoclast Differentiation

Synchronized Cell Cycle Arrest Promotes Osteoclast Differentiation

Osteoclast progenitors undergo cell cycle arrest before differentiation into osteoclasts, induced by exposure to macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL). The role of such cell cycle arrest in osteoclast differentiation has remained uncl...

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Bibliographic Details
Main Authors: Minsuk Kwon, Jin-Man Kim, Kyunghee Lee, So-Young Park, Hyun-Sook Lim, Taesoo Kim, Daewon Jeong
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
cell cycle arrest
cell synchronization
osteoclast differentiation
Online Access:http://www.mdpi.com/1422-0067/17/8/1292

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http://www.mdpi.com/1422-0067/17/8/1292

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