A Novel Optical Tissue Clearing Protocol for Mouse Skeletal Muscle to Visualize Endplates in Their Tissue Context

A Novel Optical Tissue Clearing Protocol for Mouse Skeletal Muscle to Visualize Endplates in Their Tissue Context

Neuromuscular junctions (NMJs) mediate skeletal muscle contractions and play an important role in several neuromuscular disorders when their morphology and function are compromised. However, due to their small size and sparse distribution throughout the comparatively large, inherently opaque muscle...

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Bibliographic Details
Main Authors: Marion Patrick Ivey Williams, Matteo Rigon, Tatjana Straka, Sarah Janice Hörner, Manfred Thiel, Norbert Gretz, Mathias Hafner, Markus Reischl, Rüdiger Rudolf
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
acetylcholine receptor
hydrogel embedding
NMJ
optical tissue clearing
skeletal muscle
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00049/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00049/full

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