Pharmacophore modeling and 3D QSAR studies of aryl amine derivatives as potential lumazine synthase inhibitors

Design and discovery of novel antifungal compounds is the need of time, more than ever before due to the unavailability of effective antifungal therapy to treat resistant fungal infections. Due to morphological and functional similarities of fungi both with plant cell and human cell, the search for...

Full description

Bibliographic Details
Main Authors: Manish S. Bhatia, Krishna D. Pakhare, Prafulla B. Choudhari, Swapnil D. Jadhav, Rakesh P. Dhavale, Neela M. Bhatia
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535212001657