Partially penetrant postnatal lethality of an epithelial specific MicroRNA in a mouse knockout.

MicroRNAs are small noncoding RNAs thought to have pivotal roles in numerous diseases and developmental processes. However, a growing body of literature indicates that in vivo elimination of these tiny RNAs usually has little to no observable consequence, suggesting functional redundancy with other...

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Bibliographic Details
Main Authors: D'Juan T Farmer, Nikki Shariat, Chong Yon Park, Huey Jiin Liu, Anastasia Mavropoulos, Michael T McManus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792019?pdf=render