The spleen CD4+ T cell response to blood-stage Plasmodium chabaudi malaria develops in two phases characterized by different properties.

The pivotal role of spleen CD4(+) T cells in the development of both malaria pathogenesis and protective immunity makes necessary a profound comprehension of the mechanisms involved in their activation and regulation during Plasmodium infection. Herein, we examined in detail the behaviour of non-con...

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Bibliographic Details
Main Authors: Sandra Marcia Muxel, Ana Paula Freitas do Rosário, Cláudia Augusta Zago, Sheyla Inés Castillo-Méndez, Luiz Roberto Sardinha, Sérgio Marcelo Rodriguez-Málaga, Niels Olsen Saraiva Câmara, José Maria Álvarez, Maria Regina D'Império Lima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3141041?pdf=render