β-1,3-glucan-lacking Aspergillus fumigatus mediates an efficient antifungal immune response by activating complement and dendritic cells

β-1,3-glucan-lacking Aspergillus fumigatus mediates an efficient antifungal immune response by activating complement and dendritic cells

Complement system and dendritic cells (DCs) form – beside neutrophils and macrophages – the first line of defense to combat fungal infections. Therefore, we here studied interactions of these first immune elements with Aspergillus fumigatus lacking ß-1,3-glucans (fks1tetOnrep under repressed conditi...

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Bibliographic Details
Main Authors: Marion Steger, Marta Bermejo-Jambrina, Teodor Yordanov, Johannes Wagener, Axel A Brakhage, Verena Pittl, Lukas A Huber, Hubertus Haas, Cornelia Lass-Flörl, Wilfried Posch, Doris Wilflingseder
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Virulence
Subjects:
fungal infection
dendritic cell
complement
t helper cells
β-1
3-glucan
Online Access:http://dx.doi.org/10.1080/21505594.2018.1528843

Internet

http://dx.doi.org/10.1080/21505594.2018.1528843

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