Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1.

Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1.

Neglected tropical diseases, including diseases caused by trypanosomatid parasites such as Trypanosoma brucei, cost tens of millions of disability-adjusted life-years annually. As the current treatments for African trypanosomiasis and other similar infections are limited, new therapeutics are urgent...

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Bibliographic Details
Main Authors: Jacob D Durrant, Laurence Hall, Robert V Swift, Melissa Landon, Achim Schnaufer, Rommie E Amaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2927429?pdf=render

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http://europepmc.org/articles/PMC2927429?pdf=render

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