Novel Molecular Hallmarks of Group 3 Medulloblastoma by Single-Cell Transcriptomics

Novel Molecular Hallmarks of Group 3 Medulloblastoma by Single-Cell Transcriptomics

Medulloblastoma (MB) is a highly heterogeneous and one of the most malignant pediatric brain tumors, comprising four subgroups: Sonic Hedgehog, Wingless, Group 3, and Group 4. Group 3 MB has the worst prognosis of all MBs. However, the molecular and cellular mechanisms driving the maintenance of mal...

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Bibliographic Details
Main Authors: Chaoying Qin, Yimin Pan, Yuzhe Li, Yue Li, Wenyong Long, Qing Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
group 3 medulloblastoma
single-cell sequencing
hallmark
prognosis
molecular cascades
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.622430/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.622430/full

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