Honeybee Royal Jelly and Nobiletin Stimulate CRE-Mediated Transcription in ERK-Independent and -Dependent Fashions, Respectively, in PC12D Cells

Honeybee Royal Jelly and Nobiletin Stimulate CRE-Mediated Transcription in ERK-Independent and -Dependent Fashions, Respectively, in PC12D Cells

Abstract.: To prove the pharmacological actions of honeybee royal jelly (RJ) on the nervous system, we examined the effects of RJ on CRE-mediated transcription. RJ increased CRE-mediated transcription in PC12D cells. Moreover, CRE-mediated transcriptional activity by RJ was enhanced by nobiletin. U0...

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Bibliographic Details
Main Authors: Hironori Fujiwara, Ako Kogure, Masahiro Sakamoto, Tohru Yamakuni, Yoshihiro Mimaki, Kiyoshi Murata, Nobuyuki Hitomi, Kikuji Yamaguchi, Yasushi Ohizumi
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319306772

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http://www.sciencedirect.com/science/article/pii/S1347861319306772

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