TACI Contributes to Plasmodium yoelii Host Resistance by Controlling T Follicular Helper Cell Response and Germinal Center Formation

TACI Contributes to Plasmodium yoelii Host Resistance by Controlling T Follicular Helper Cell Response and Germinal Center Formation

The delay in parasite-specific B cell development leaves people in malaria endemic areas vulnerable to repeated Plasmodium infections. Here, we investigated the role of transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI), a molecule involved in the generation of an...

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Bibliographic Details
Main Authors: Marcela Parra, Jiyeon Yang, Megan Weitner, Steven Derrick, Amy Yang, Thomas Schmidt, Balwan Singh, Alberto Moreno, Mustafa Akkoyunlu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
Plasmodium yoelii
TACI
T follicular helper cell
Germinal center
B cell
antibody
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02612/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02612/full

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