Methylglyoxal attenuates isoproterenol-induced increase in uncoupling protein 1 expression through activation of JNK signaling pathway in beige adipocytes

Methylglyoxal (MG) is a metabolite derived from glycolysis whose levels in the blood and tissues of patients with diabetes are higher than those of healthy individuals, suggesting that MG is associated with the development of diabetic complications. However, it remains unknown whether high levels of...

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Bibliographic Details
Main Authors: Su-Ping Ng, Wataru Nomura, Haruya Takahashi, Kazuo Inoue, Teruo Kawada, Tsuyoshi Goto
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
JNK
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821002211