The importance of cellular and exosomal miRNAs in mesenchymal stem cell osteoblastic differentiation

Abstract The differentiation of osteoblasts is under complex regulation that includes autocrine and paracrine signaling from MSCs. Exosomes are important components of the MSC secretome and their cargo contains numerous miRNAs. In this study, the importance of MSC miRNAs in modulation of osteoblasti...

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Bibliographic Details
Main Authors: Sajjad Shirazi, Chun-Chieh Huang, Miya Kang, Yu Lu, Sriram Ravindran, Lyndon F. Cooper
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85306-2