In-depth characterization of a mouse model of post-traumatic epilepsy for biomarker and drug discovery

Abstract Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies and 10–20% of the acquired forms. The latency between traumatic brain injury (TBI) and epilepsy onset in high-risk patients offers a therapeutic window for intervention to prevent or improve the disease course. However, progres...

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Bibliographic Details
Main Authors: Rossella Di Sapia, Federico Moro, Marica Montanarella, Valentina Iori, Edoardo Micotti, Daniele Tolomeo, Kevin K. W. Wang, Annamaria Vezzani, Teresa Ravizza, Elisa R. Zanier
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Acta Neuropathologica Communications
Online Access:https://doi.org/10.1186/s40478-021-01165-y