Determination of EGFR endocytosis kinetic by auto-regulatory association of PLD1 with mu2.

BACKGROUND:Upon ligand binding, cell surface signaling receptors are internalized through a process tightly regulated by endocytic proteins and adaptor protein 2 (AP2) to orchestrate them. Although the molecular identities and roles of endocytic proteins are becoming clearer, it is still unclear wha...

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Bibliographic Details
Main Authors: Jun Sung Lee, Il Shin Kim, Jung Hwan Kim, Wonhwa Cho, Pann-Ghill Suh, Sung Ho Ryu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2739277?pdf=render