THE POSSIBILITIES AND MECHANISMS OF ACTION OF HORMONE THERAPY FOR CASTRATION-RESISTANT PROSTATE CANCER

Hormone therapy is a basic treatment for locally advanced and/or metastatic prostate cancer (PC); however, most patients become resistant to first-line therapy in the course of time. Abiraterone is a highly active, selective, irreversible CYP17 inhibitor that prevents the conversion of pregnenolone...

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Bibliographic Details
Main Authors: B. Ya. Alekseev, A. N. Andrianov
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Onkourologiâ
Subjects:
Online Access:https://oncourology.abvpress.ru/oncur/article/view/197