Understanding the Effect of Multiple Domain Deletion in DNA Polymerase I from <i>Geobacillus</i> Sp. Strain SK72

Understanding the Effect of Multiple Domain Deletion in DNA Polymerase I from <i>Geobacillus</i> Sp. Strain SK72

The molecular structure of DNA polymerase I or family A polymerases is made up of three major domains that consist of a single polymerase domain with two extra exonuclease domains. When the N-terminal was deleted, the enzyme was still able to perform basic polymerase activity with additional traits...

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Bibliographic Details
Main Authors: Waqiyuddin Hilmi Hadrawi, Anas Norazman, Fairolniza Mohd Shariff, Mohd Shukuri Mohamad Ali, Raja Noor Zaliha Raja Abd Rahman
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Catalysts
Subjects:
SK72 DNA polymerase I
polymerase domain
5′-3′ exonuclease domain
3′-5′ exonuclease domain
proofreading activity
Online Access:https://www.mdpi.com/2073-4344/10/8/936

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https://www.mdpi.com/2073-4344/10/8/936

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