Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier

Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier

For glioblastoma, the tumor microenvironment (TME) is pivotal to support tumor progression and therapeutic resistance. TME consists of several types of stromal, endothelial and immune cells, which are recruited by cancer stem cells (CSCs) to influence CSC phenotype and behavior. TME also promotes th...

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Bibliographic Details
Main Authors: Martina Da Ros, Veronica De Gregorio, Anna Lisa Iorio, Laura Giunti, Milena Guidi, Maurizio de Martino, Lorenzo Genitori, Iacopo Sardi
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
chemoresistance
microenvironment
blood-brain barrier
Online Access:http://www.mdpi.com/1422-0067/19/10/2879

Internet

http://www.mdpi.com/1422-0067/19/10/2879

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