A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster

A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster

Due to their strict maternal inheritance in most animals and plants, mitochondrial genomes are predicted to accumulate mutations that are beneficial or neutral in females but harmful in males. Although a few male-harming mtDNA mutations have been identified, consistent with this ‘Mother’s Curse’, th...

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Bibliographic Details
Main Authors: Maulik R Patel, Ganesh K Miriyala, Aimee J Littleton, Heiko Yang, Kien Trinh, Janet M Young, Scott R Kennedy, Yukiko M Yamashita, Leo J Pallanck, Harmit S Malik
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
mitochondrial DNA
experimental evolution
male fertility
sperm development
lifespan
genetic suppressors
Online Access:https://elifesciences.org/articles/16923

Internet

https://elifesciences.org/articles/16923

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