Differentiation of primordial germ cells from premature ovarian insufficiency-derived induced pluripotent stem cells

Abstract Background Premature ovarian insufficiency (POI) is a common disease in reproductive women. The pathogenesis of POI is not clear, although it is known that it involves the disorder of oocyte differentiation and development. The introduction of reprogramming human somatic cells into induced...

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Bibliographic Details
Main Authors: Sheng Yang, Shufang Ding, Shiwei He, Lixia He, Kefei Gao, Shuping Peng, Cijun Shuai
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-019-1261-6