Down‐regulation of PDGFRβ suppresses invasion and migration in osteosarcoma cells by influencing epithelial–mesenchymal transition

Down‐regulation of PDGFRβ suppresses invasion and migration in osteosarcoma cells by influencing epithelial–mesenchymal transition

Osteosarcoma (OS) is the most common malignant bone tumor primarily influencing children and adults. Approximately one‐fifth of patients have micrometastasis in the lungs when OS is diagnosed. Platelet‐derived growth factor receptor (PDGFR) beta (PDGFRβ) is a subtype of PDGFR. PDGFRβ has been noted...

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Bibliographic Details
Main Authors: Sining Xing, Changdong Wang, Huying Tang, Jiaqi Guo, Xing Liu, Faping Yi, Geli Liu, Xiangmei Wu
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:FEBS Open Bio
Subjects:
epithelial–mesenchymal transition
invasion
migration
osteosarcoma
PDGFRβ
Online Access:https://doi.org/10.1002/2211-5463.12915

Internet

https://doi.org/10.1002/2211-5463.12915

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