Microfluidic System for In Vivo-Like Drug Permeation Studies with Dynamic Dilution Profiles

Microfluidic System for In Vivo-Like Drug Permeation Studies with Dynamic Dilution Profiles

Automated biomimetic systems for the preclinical testing of drugs are of great interest. Here, an in vitro testing platform for in vivo adapted drug absorption studies is presented. It has been designed with a focus on easy handling and the usability of established cell cultivation techniques in sta...

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Bibliographic Details
Main Authors: Thomas Lorenz, Mona Kirschke, Verena Ledwig, Stephan Reichl, Andreas Dietzel
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Bioengineering
Subjects:
drug testing
in vitro
sodium fluorescein
MDCK
microfluidic test system
organ-on-chip
Online Access:https://www.mdpi.com/2306-5354/8/5/58

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https://www.mdpi.com/2306-5354/8/5/58

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