Structural Investigation and Molecular Modeling Studies of Strobilurin-Based Fungicides Active against the Rice Blast Pathogen <i>Pyricularia oryzae</i>

Structural Investigation and Molecular Modeling Studies of Strobilurin-Based Fungicides Active against the Rice Blast Pathogen <i>Pyricularia oryzae</i>

The increasing emergence of fungicide-resistant pathogens requires urgent solutions for crop disease management. Here, we describe a structural investigation of new fungicides obtained by combining strobilurin and succinate dehydrogenase inhibitor pharmacophores. We identified compounds endowed with...

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Bibliographic Details
Main Authors: Andrea Kunova, Luca Palazzolo, Fabio Forlani, Giorgia Catinella, Loana Musso, Paolo Cortesi, Ivano Eberini, Andrea Pinto, Sabrina Dallavalle
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
rice blast
crop protection
cytochrome <i>bc1</i> complex
antifungal compounds
homology modeling
molecular docking
Online Access:https://www.mdpi.com/1422-0067/22/7/3731

Internet

https://www.mdpi.com/1422-0067/22/7/3731

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