Overexpression of miR-155 in the liver of transgenic mice alters the expression profiling of hepatic genes associated with lipid metabolism.

Overexpression of miR-155 in the liver of transgenic mice alters the expression profiling of hepatic genes associated with lipid metabolism.

Hepatic expression profiling has revealed miRNA changes in liver diseases, while hepatic miR-155 expression was increased in murine non-alcoholic fatty liver disease, suggesting that miR-155 might regulate the biological process of lipid metabolism. To illustrate the effects of miR-155 gain of funct...

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Bibliographic Details
Main Authors: Xiaolin Lin, Junshuang Jia, Tao Du, Wei Li, Xiaoyan Wang, Jieqiong Wei, Xia Lin, Hui Zeng, Longping Yao, Xuebing Chen, Jingshen Zhuang, Jie Weng, Yu Liu, Jihong Lin, Qinghong Wu, Wanshan Wang, Kaitai Yao, Kang Xu, Dong Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4370457?pdf=render

Internet

http://europepmc.org/articles/PMC4370457?pdf=render

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