Hematopoietic Stem Cell Niches and Signals Controlling Immune Cell Development and Maintenance of Immunological Memory

Hematopoietic Stem Cell Niches and Signals Controlling Immune Cell Development and Maintenance of Immunological Memory

Studies over the last couple of decades have shown that hematopoietic stem cells (HSCs) are critically dependent on cytokines such as Stem Cell Factor and other signals provided by bone marrow niches comprising of mesenchymal stem and progenitor cells (MSPCs) and endothelial cells (ECs). Because of...

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Bibliographic Details
Main Authors: Runfeng Miao, Vivian Y. Lim, Neeharika Kothapalli, Yifan Ma, Julia Fossati, Sandra Zehentmeier, Ruifeng Sun, João P. Pereira
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
hematopoietic stem cell niches
lymphopoiesis
myelopoiesis
CXCR4
WHIM syndrome
leukemia
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.600127/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.600127/full

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