Structure-reactivity relationships on Michael additions of secondary cyclic amines with 3-cyanomethylidene-2-oxindoline derivatives

A kinetic study of the nucleophilic addition reactions of 3-cyanomethylidene-2-oxindoline derivatives with cyclic amines (namely: piperidine, morpholine and pyrrolidine) in MeCN solution at 20 °C is reported. The second-order rate constants showed of this process fit nicely the Brönsted equation log...

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Bibliographic Details
Main Authors: Shaimaa Sindi, Nizar El Guesmi, Basim H. Asghar, Essam M. Hussein
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535220301027