Thapsigargin-Stimulated LAD2 Human Mast Cell Line Is a Potent Cellular Adjuvant for the Maturation of Monocyte-Derived Dendritic Cells for Adoptive Cellular Immunotherapy

Thapsigargin-Stimulated LAD2 Human Mast Cell Line Is a Potent Cellular Adjuvant for the Maturation of Monocyte-Derived Dendritic Cells for Adoptive Cellular Immunotherapy

The preparation of dendritic cells (DCs) for adoptive cellular immunotherapy (ACI) requires the maturation of ex vivo-produced immature(i) DCs. This maturation ensures that the antigen presentation triggers an immune response towards the antigen-expressing cells. Although there is a large number of...

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Bibliographic Details
Main Authors: Pavla Taborska, Dmitry Stakheev, Jirina Bartunkova, Daniel Smrz
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
LAD2 human mast cells
dendritic cells
maturation
adoptive cellular immunotherapy
Online Access:https://www.mdpi.com/1422-0067/22/8/3978

Internet

https://www.mdpi.com/1422-0067/22/8/3978

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