Viral and Cellular Requirements for the Nuclear Entry of Retroviral Preintegration Nucleoprotein Complexes

Retroviruses integrate their reverse transcribed genomes into host cell chromosomes as an obligate step in virus replication. The nuclear envelope separates the chromosomes from the cell cytoplasm during interphase, and different retroviral groups deal with this physical barrier in different ways. G...

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Bibliographic Details
Main Authors: Alan Engelman, Kenneth A. Matreyek
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Viruses
Subjects:
HIV
Online Access:http://www.mdpi.com/1999-4915/5/10/2483