The Transcriptional Regulators of the CRP Family Regulate Different Essential Bacterial Functions and Can Be Inherited Vertically and Horizontally

The Transcriptional Regulators of the CRP Family Regulate Different Essential Bacterial Functions and Can Be Inherited Vertically and Horizontally

One of the best-studied transcriptional regulatory proteins in bacteria is the Escherichia coli catabolite repressor protein (CRP) that when complexed with 3′-5′-cyclic AMP (cAMP) changes its conformation and interacts with specific DNA-sequences. CRP DNA-binding can result in positive or negative r...

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Bibliographic Details
Main Authors: Gloria Soberón-Chávez, Luis D. Alcaraz, Estefanía Morales, Gabriel Y. Ponce-Soto, Luis Servín-González
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Microbiology
Subjects:
CRP-orthologs
core-genome
pan-genome
horizontal gene transfer
bacterial-evolution
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.00959/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.00959/full

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