WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1

WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1

Abstract Background N6-methyladenosine (m6A) methylation, a well-known modification with new epigenetic functions, has been reported to participate in the tumorigenesis of hepatocellular carcinoma (HCC), providing novel insights into the molecular pathogenesis of this disease. However, as the key co...

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Bibliographic Details
Main Authors: Yunhao Chen, Chuanhui Peng, Junru Chen, Diyu Chen, Beng Yang, Bin He, Wendi Hu, Yanpeng Zhang, Hua Liu, Longfei Dai, Haiyang Xie, Lin Zhou, Jian Wu, Shusen Zheng
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Molecular Cancer
Subjects:
N6-methyladenosine (m6A)
Wilms tumor 1-associated protein (WTAP)
Hepatocellular carcinoma (HCC)
ETS1
Online Access:http://link.springer.com/article/10.1186/s12943-019-1053-8

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http://link.springer.com/article/10.1186/s12943-019-1053-8

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