Stereotaxical infusion of rotenone: a reliable rodent model for Parkinson's disease.

A clinically-related animal model of Parkinson's disease (PD) may enable the elucidation of the etiology of the disease and assist the development of medications. However, none of the current neurotoxin-based models recapitulates the main clinical features of the disease or the pathological hal...

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Main Authors: Nian Xiong, Jinsha Huang, Zhentao Zhang, Zhaowen Zhang, Jing Xiong, Xingyuan Liu, Min Jia, Fang Wang, Chunnuan Chen, Xuebing Cao, Zhihou Liang, Shenggang Sun, Zhicheng Lin, Tao Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2774159?pdf=render