WIP regulates persistence of cell migration and ruffle formation in both mesenchymal and amoeboid modes of motility.

WIP regulates persistence of cell migration and ruffle formation in both mesenchymal and amoeboid modes of motility.

The spatial distribution of signals downstream from receptor tyrosine kinases (RTKs) or G-protein coupled receptors (GPCR) regulates fundamental cellular processes that control cell migration and growth. Both pathways rely significantly on actin cytoskeleton reorganization mediated by nucleation-pro...

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Bibliographic Details
Main Authors: Inmaculada Banon-Rodriguez, Julia Saez de Guinoa, Alejandra Bernardini, Chiara Ragazzini, Estefania Fernandez, Yolanda R Carrasco, Gareth E Jones, Francisco Wandosell, Ines Maria Anton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3737202?pdf=render

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http://europepmc.org/articles/PMC3737202?pdf=render

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