Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes

In mammals, the testis-specific bromodomain and extra terminal (BET) protein BRDT is essential for spermatogenesis. In Drosophila, it was recently reported that the tBRD-1 protein is similarly required for male fertility. Interestingly, however, tBRD-1 has two conserved bromodomains in its N-terminu...

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Bibliographic Details
Main Authors: Shuhei Kimura, Benjamin Loppin
Format: Article
Language:English
Published: The Royal Society 2015-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.140145