MicroRNAs Expression Induces Apoptosis of Macrophages in Response to Leishmania major (MRHO/IR/75/ER): An In-Vitro and In-Vivo Study

MicroRNAs Expression Induces Apoptosis of Macrophages in Response to Leishmania major (MRHO/IR/75/ER): An In-Vitro and In-Vivo Study

Background: We aimed to investigate the effect of miR-15a mimic and inhibitor of miR-155 expression on apoptosis induction in macrophages infected with Iranian strain of Leishmania major in-vitro and in-vivo. Methods: RAW 264.7 cells were infected with L. major promastigotes (MRHO/IR/75/ER), and...

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Bibliographic Details
Main Authors: Mostafa GHOLAMREZAEI, Soheila ROUHANI, Mehdi MOHEBALI, Samira MOHAMMADI-YEGANEH, Mostafa HAJI MOLLA HOSEINI, Ali HAGHIGHI, Zohreh LASJERDI, Faezeh HAMIDI, Mohammad KAZEM SHARIFI-YAZDI
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-12-01
Series:Iranian Journal of Parasitology
Subjects:
Leishmania major
Apoptosis
microRNAs
In vitro
In vivo
Online Access:https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3168

Internet

https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3168

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