Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth.

cAMP-dependent protein kinase (PKA) has been implicated in the asexual stage of the Toxoplasma gondii life cycle through assaying the effect of a PKA-specific inhibitor on its growth rate. Since inhibition of the host cell PKA cannot be ruled out, a more precise evaluation of the role of PKA, as wel...

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Main Authors: Hitomi Kurokawa, Kentaro Kato, Tatsuya Iwanaga, Tatsuki Sugi, Atsushi Sudo, Kyousuke Kobayashi, Haiyan Gong, Hitoshi Takemae, Frances C Recuenco, Taisuke Horimoto, Hiroomi Akashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3140512?pdf=render